| 2007-11-09 | Joint reporting: BB BIOVENTURES L P; MPM BIOVENTURES PARALLEL FUND L P; BAB BIO VENTURES LLP; BAB BIO VENTURES NV; MPM BIOVENTURES I LP; MPM BIO VENTURES I LLC; MPM ASSET MANAGEMENT INVESTORS 2000A LLC | U | $36.3M |
| 2007-11-09 | Joint reporting: GADICKE ANSBERT; STEINMETZ MICHAEL; GALAKATOS NICHOLAS; WHEELER KURT; MPM ASSET MANAGEMENT INVESTORS 2001 LLC; MPM ASSET MANAGEMENT II LP; MPM ASSET MANAGEMENT II LLC; MPM BIOVENTURES II LP; MPM BIOVENTURES II QP LP; MPM BIOVENTURES GMBH & CO PARALLEL BETEILIGUNGS KG | U | $36.3M |
| 2007-11-09 | Joint reporting: EVNIN LUKE; MPM Founders LLC | U | $36.3M |
| 2007-11-09 | Joint reporting: BIOTECHNOLOGY VALUE FUND L P; BVF PARTNERS L P/IL; BVF INC/IL; BIOTECHNOLOGY VALUE FUND II LP; BVF INVESTMENTS LLC | Sell | $32.4M |
| 2007-11-09 | Joint reporting: BIOTECHNOLOGY VALUE FUND L P; BVF PARTNERS L P/IL; BVF INC/IL; BIOTECHNOLOGY VALUE FUND II LP; BVF INVESTMENTS LLC | Sell | $12.2M |
| 2007-11-09 | Joint reporting: BIOTECHNOLOGY VALUE FUND L P; BVF PARTNERS L P/IL; BVF INC/IL; BIOTECHNOLOGY VALUE FUND II LP; BVF INVESTMENTS LLC | Sell | $8.3M |
| 2007-11-09 | Joint reporting: BB BIOVENTURES L P; MPM BIOVENTURES PARALLEL FUND L P; BAB BIO VENTURES LLP; BAB BIO VENTURES NV; MPM BIOVENTURES I LP; MPM BIO VENTURES I LLC; MPM ASSET MANAGEMENT INVESTORS 2000A LLC | U | $2.4M |
| 2007-11-09 | Joint reporting: GADICKE ANSBERT; STEINMETZ MICHAEL; GALAKATOS NICHOLAS; WHEELER KURT; MPM ASSET MANAGEMENT INVESTORS 2001 LLC; MPM ASSET MANAGEMENT II LP; MPM ASSET MANAGEMENT II LLC; MPM BIOVENTURES II LP; MPM BIOVENTURES II QP LP; MPM BIOVENTURES GMBH & CO PARALLEL BETEILIGUNGS KG | U | $2.4M |
| 2007-11-09 | Joint reporting: EVNIN LUKE; MPM Founders LLC | U | $2.4M |
| 2007-11-09 | Joint reporting: BB BIOVENTURES L P; MPM BIOVENTURES PARALLEL FUND L P; BAB BIO VENTURES LLP; BAB BIO VENTURES NV; MPM BIOVENTURES I LP; MPM BIO VENTURES I LLC; MPM ASSET MANAGEMENT INVESTORS 2000A LLC | U | $949K |
| 2007-11-09 | Joint reporting: GADICKE ANSBERT; STEINMETZ MICHAEL; GALAKATOS NICHOLAS; WHEELER KURT; MPM ASSET MANAGEMENT INVESTORS 2001 LLC; MPM ASSET MANAGEMENT II LP; MPM ASSET MANAGEMENT II LLC; MPM BIOVENTURES II LP; MPM BIOVENTURES II QP LP; MPM BIOVENTURES GMBH & CO PARALLEL BETEILIGUNGS KG | U | $949K |
| 2007-11-09 | Joint reporting: BB BIOVENTURES L P; MPM BIOVENTURES PARALLEL FUND L P; BAB BIO VENTURES LLP; BAB BIO VENTURES NV; MPM BIOVENTURES I LP; MPM BIO VENTURES I LLC; MPM ASSET MANAGEMENT INVESTORS 2000A LLC | U | $334K |
| 2007-11-09 | Joint reporting: GADICKE ANSBERT; STEINMETZ MICHAEL; GALAKATOS NICHOLAS; WHEELER KURT; MPM ASSET MANAGEMENT INVESTORS 2001 LLC; MPM ASSET MANAGEMENT II LP; MPM ASSET MANAGEMENT II LLC; MPM BIOVENTURES II LP; MPM BIOVENTURES II QP LP; MPM BIOVENTURES GMBH & CO PARALLEL BETEILIGUNGS KG | U | $334K |
| 2007-11-09 | Joint reporting: BB BIOVENTURES L P; MPM BIOVENTURES PARALLEL FUND L P; BAB BIO VENTURES LLP; BAB BIO VENTURES NV; MPM BIOVENTURES I LP; MPM BIO VENTURES I LLC; MPM ASSET MANAGEMENT INVESTORS 2000A LLC | U | $183K |
| 2007-11-09 | Joint reporting: GADICKE ANSBERT; STEINMETZ MICHAEL; GALAKATOS NICHOLAS; WHEELER KURT; MPM ASSET MANAGEMENT INVESTORS 2001 LLC; MPM ASSET MANAGEMENT II LP; MPM ASSET MANAGEMENT II LLC; MPM BIOVENTURES II LP; MPM BIOVENTURES II QP LP; MPM BIOVENTURES GMBH & CO PARALLEL BETEILIGUNGS KG | U | $183K |
| 2007-11-09 | Joint reporting: EVNIN LUKE; MPM Founders LLC | U | $183K |
| 2007-11-09 | Joint reporting: BB BIOVENTURES L P; MPM BIOVENTURES PARALLEL FUND L P; BAB BIO VENTURES LLP; BAB BIO VENTURES NV; MPM BIOVENTURES I LP; MPM BIO VENTURES I LLC; MPM ASSET MANAGEMENT INVESTORS 2000A LLC | U | $105K |
| 2007-11-09 | Joint reporting: GADICKE ANSBERT; STEINMETZ MICHAEL; GALAKATOS NICHOLAS; WHEELER KURT; MPM ASSET MANAGEMENT INVESTORS 2001 LLC; MPM ASSET MANAGEMENT II LP; MPM ASSET MANAGEMENT II LLC; MPM BIOVENTURES II LP; MPM BIOVENTURES II QP LP; MPM BIOVENTURES GMBH & CO PARALLEL BETEILIGUNGS KG | U | $105K |
| 2007-11-09 | Joint reporting: BB BIOVENTURES L P; MPM BIOVENTURES PARALLEL FUND L P; BAB BIO VENTURES LLP; BAB BIO VENTURES NV; MPM BIOVENTURES I LP; MPM BIO VENTURES I LLC; MPM ASSET MANAGEMENT INVESTORS 2000A LLC | U | $20K |
| 2007-11-09 | Joint reporting: GADICKE ANSBERT; STEINMETZ MICHAEL; GALAKATOS NICHOLAS; WHEELER KURT; MPM ASSET MANAGEMENT INVESTORS 2001 LLC; MPM ASSET MANAGEMENT II LP; MPM ASSET MANAGEMENT II LLC; MPM BIOVENTURES II LP; MPM BIOVENTURES II QP LP; MPM BIOVENTURES GMBH & CO PARALLEL BETEILIGUNGS KG | U | $20K |