Spyre Therapeutics, Inc.

Lobbying Spend

—

Filings

Firms Hired

Active Period

2025–2026

Lobbying Spend by Year

Client-reported lobbying expenses on LDA filings

Year	Lobbying Spend	Filings	Firms
2026	—	3	1
2025	—	2	1

Lobbying firms retained by this client; amounts are client-reported expenses when available

Firm Name	Reported Spend	Filings
ARNOLD & PORTER KAYE SCHOLER LLP	—	5

Government entities explicitly identified as targets in LDA filings

Government Body	Filings
HOUSE OF REPRESENTATIVES	4
SENATE	4
Executive Office of the President (EOP)	1
Food & Drug Administration (FDA)	1
Office of Management & Budget (OMB)	1

Most frequently reported lobbying issues

Issue Code	Description	Reports
Health Issues	Health Issues	5
Pharmacy	Pharmacy	1
Medical/Disease Research/Clinical Labs	Medical/Disease Research/Clinical Labs	1

Spyre Therapeutics, Inc. — Lobbying Disclosure | Poliscope